It's a mistake to underestimate the power of sleep. The former
British prime minister Margaret Thatcher once proclaimed she slept
only four hours a night. In other words, sleep was for wimps. What she
didn't tell us was that years and years of too little sleep eventually
takes its toll on our health and possibly causes premature death.
About 30 per cent of Australians will experience sleep disorders
during their lives, from insomnia to sleep apnoea, which is linked to
cardiovascular problems. Many more will experience pervasive
tiredness, propping themselves up with caffeine or sugar.
Business is thriving for Sydney's private sleep clinics, which
treat an increasing number of people with sleep disorders. They
include those affected by world events such as the Iraq war or
professionals who find the stresses of work prevent them "switching
off"' at night.
Sleep clinics record your brain waves, heart rate and breathing
while you sleep. The next day, your sleep is mapped and analysed and
used as a guide to help diagnose any sleeping disorder.
SLEEP APNOEA
Obstructive Sleep Apnoea (OSA) is the most common sleep disorder in
Australia. If untreated, consequences vary from tiredness to premature
death.
The sleeper stops breathing for up to two minutes until the body's
defence mechanism causes them to wake and breathe normally again. In
its mild form, OSA is characterised by snoring and results in
disturbed sleep and daytime tiredness. In more severe cases it can
lead to obesity, hypertension, bladder problems and death from
cardiovascular disease.
Sleep physician Dr Shu Chan says sufferers choke and cease
breathing due to obstruction in the throat, which occurs when the
muscles controlling the tongue and soft palate relax and the airways
narrow. The brain reacts to this oxygen deficiency and alerts the body
to wake up. This arousal can happen hundreds of times every night.
Sufferers usually feel sleepy and lethargic the next day.
Sleep specialists Dr David Jankelson, at St Vincent's Hospital, and
Dr Ron Grunstein, at Royal Prince Alfred (RPA), say it's the most
common sleep disorder they treat.
A 1995 study by RPA found OSA affects more than 10 per cent of
middle-aged men and 5 per cent of women.
The study notes that this figure is "likely to be a substantial
underestimate with the real figure probably being nearer to 30 per
cent".
Chan says "the figures are sure to be much larger. Men do not
complain, so their sleep apnoea is hidden."
Lack of funding in the area means "we do not have the resources to
do the type of comprehensive surveys we need to get the full picture
of sleep in Australia," he says.
At St Vincent's, 60 per cent of people treated for sleep disorders
have OSA and "the rest would be movement disorder [Restless Leg
Syndrome] and respiratory failure," says Jankelson.
Grunstein says OSA is often misdiagnosed and "very much
misunderstood". "A lot people don't know what it is [and] sufferers
are regarded as lazy, when they are not," he says.
Jankelson says it's not a disorder to be complacent about: "Sleep
apnoea has been linked to excessive daytime sleepiness, mood change,
irritability, depression and an increased risk of having a motor
vehicle accident."
The Medical Journal of Australia recently reported that OSA
can increase the risk of accidents by two to seven times.
Chan says many of his patients operate machinery or vehicles, such
as train drivers, pilots and defence force personnel. If diagnosed
with OSA, they are usually given modified work duties.
Chan calls it adult cot death. "They either recover or have severe
problems if sleep apnoea is coupled with chronic lung disease and die
in about five years.
"For a lot of sufferers, it is pot luck if you see a GP who knows a
respiratory physician. If you live in Sydney and Melbourne you might
be lucky but if you live in a regional area it could go unrecognised,"
he says.
Chan's gloomy prediction for some OSA sufferers is based on
research that links the disorder to cardiovascular risks factors,
known as "syndrome X" or metabolic dysfunction, which describes a
group of related conditions such as insulin resistance, obesity,
hypertension and elevated cholesterol.
When OSA is added to the mix, Australian sleep specialists refer to
it as "Syndrome Z".
A 2001 study at Johns Hopkins School of Medicine in the United
States found "sleep-disordered breathing was associated with impaired
glucose tolerance and insulin resistance independent of obesity.
"The implication of these findings is that the metabolic
dysfunction associated with sleep-disordered breathing may increase
the risk of cardiovascular morbidity and mortality."
Researchers at RPA found "obesity is common in OSA" sufferers and
as "body mass increases the incidence of OSA also increases and about
50 per cent of morbidly obese subjects have OSA".
Grunstein, Jankelson and Chan say further research is needed before
the link between OSA, cardiovascular disease and obesity is
watertight.
Meanwhile, treatment of OSA "is somewhat primitive", says Jankelson.
Many sufferers are prescribed a device called a CPAP (Continuous
Positive Airway Pressure), to be worn during sleep, which forces air
to the airways through a nasal mask. The upper airways are then kept
open, creating an air splint that can prevent OSA and snoring. Its
design has been streamlined over the years but is still The paper also
explored the link between obesity and OSA. considered unwieldy by
physicians and patients.
A study published last year in the American Journal of
Respiratory and Critical Care Medicine says: "On average,
one-third of patients are non-compliant with CPAP use."
The same paper, however, says use of CPAP may "have long-term
beneficial metabolic effects". The rationale that sufferers may lose
weight on CPAP arises from studies that links lack of sleep or broken
sleep to obesity.
More studies need to be done in this area but obesity can result if
there is insufficient oxygen flowing through the body during sleep,
says Chan.
The Johns Hopkins study recommends weight loss to reduce OSA:
"Because as little as 10 to 15 per cent weight loss can reduce or
eliminate sleep-disordered breathing ... and may curtail the
cardiovascular risk associated with sleep-disordered breathing."
Grunstein is exploring alternatives to CPAP: "If we had a safe
pill, everyone would be treated but we have a limited range of
treatment." If a patient is compliant then "CPAP use is 90 to 100 per
cent effective," says Jankelson.
Finding a medication is a "slow but promising" process, he says,
adding that trials are expected in Australia next year.
Other treatments include dental aids such as plastic splints or the
more invasive palatal surgery, as a last resort.
INSOMNIA
Chan's city office is near Australia Square - a favourite drinking
precinct for Sydney's stressed bankers and lawyers.
"I see the young people drinking and partying to release stress
after a hard day and I wonder how they sleep," says Chan.
Increasingly, the answer is they don't - or not very well. The
average sleep duration has decreased from nine hours in 1910 to seven
hours.
More than a third of people experience insomnia at some point but
only about 5 per cent need treatment. About two million Australians
complain of it each year, costing millions in lost productivity,
accidents and health costs.
The pressures of the workplace are often blamed but distractions,
such as a television in the bedroom, the internet and computer games,
mean the sleep we are getting is of a lesser quality. Chan sees many
young people with daytime fatigue. "These kids are subjected to too
much stimulation and there are too many things competing for their
attention."
Grunstein says that it's not just kids. "What we are seeing is a
lot of people who work from home...They get into bed with their
laptops and mobiles and do work before they go to sleep and then
wonder why they have trouble sleeping."
Chan has seen an increase in insomnia since September 11 and the
war in Iraq: "During the Iraqi war some people came in and saw me -
they had been crying and said the war was worsening their insomnia.
They would sit up all night and watch the war on cable television,
then they couldn't sleep because they are going to bed with those
images," he says.
Grunstein and Jankelson believe that most insomnia is triggered not
by external world events but by an individual's worries and anxieties.
Insomnia can lead to "reactive depression" due to the stress of not
being able to sleep, triggering a vicious cycle.
Insomnia should be "primarily managed at a GP level", says
Grunstein.
Both RPA and St Vincent's employ psychologists who specialise in
insomnia.
The trigger for insomnia can be a stressful or emotional event such
as job loss, death of a loved one or divorce.
Grunstein says treatment can include relaxation training, hypnosis,
medication and sleep restriction, where "you stimulate the sleep drive
by restricting sleep and therefore increase sleepiness".
Jankelson says the incidence of insomnia is increasing but
professional services are not keeping up with demand. "There are only
one or two sleep psychologists in the city."
He says there's much that individuals can do to help themselves.
The doctors call it "sleep hygiene", which is basically a set of rules
or behaviour that can lead to a good night's sleep.
"It's about recognising the conditions in which to sleep, such as
no drinking alcohol or coffee before bedtime and no TV in the
bedroom."
He also recommends having a regular waking time and early morning
exercise.
RESTLESS LEG SYNDROME
Restless Leg Syndrome (RLS) is a condition where the sleeper
voluntarily moves their leg in response to a tingling sensation.
Sufferers usually feel this before bedtime or when they lie down
and the sensations prevent them from relaxing and sleeping.
Chan estimates that 10 per cent of the population suffers some form
of RLS or an associated movement disorder.
Treatment is relatively simple using medication, says Chan.
NARCOLEPSY
The most serious of the sleep disorders, narcolepsy is a rarity,
affecting about 0.05 per cent of adults worldwide. It causes a person
to fall asleep without warning. Often the trigger is heightened
emotions such as surprise or anger.
Sufferers are treated with amphetamines and Ritalin to keep them
alert. A new medication, Modafilil, that promotes wakefulness without
the stimulant effect, may provide some relief.
The waking hours
Drinking a few glasses of wine before bed doesn't help you sleep.
Instead, it's more likely to interfere with normal sleep patterns, as
I discovered when I spent a night in a private inner-city clinic that
tests for sleep disorders.
After I arrived at 9pm, two technicians spent 90 minutes preparing
me - they put glue in my hair, stuck electrodes to my scalp, suckered
them to my forehead and inserted tubes up my nose. Wires across my
fingers, legs, feet, chest and waist attached to a machine that
pulsated and hummed through the night felt like a tight leash.
Trained on my bed was an infra-red camera and microphone, monitored
by a technologist in the next room, who could hear the beating of my
heart and watch as I struggled with a heavy quilt.
Jagged brain wave readings recorded the hours spent without sleep.
At 3.30am, uncomfortable, anxious and still awake, I rolled over
and pulled out the cords attached to the machine. The technologist ran
in and reconnected me.
At 6am breakfast was served. I had slept a measly 103 minutes, in
which time the machines picked up a mild case of sleep apnoea.
Expect to pay up to $495 a night for a bed in a private clinic.
Medicare and private health funds only cover the pre- and post-sleep
consultations.
Stays at St Vincent Hospital's sleep centre are covered by Medicare
or private health funds but there is about a four-week wait for a bed.
Patients are referred to the clinic by their doctor.
Brigid Delaney